Rhinovirus Biology, Antigenic Diversity, and Advancements in the Design of a Human Rhinovirus Vaccine
Human rhinovirus (HRV) remains a leading cause of several human diseases including the common cold.Despite considerable research over the last 60 years, development of an effective vaccine to HRV has been viewed by many as unfeasible due, in part, to the antigenic diversity pentavite chewables of circulating HRVs in nature.Over 150 antigenically di